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What is Cissus Quadrangularis Supplement?

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Dietitian Pooja Maheshwari
Research Dietician, CDE, N.D.D.Y.

Cissus Quadrangularis supplements also known as hadjod are an age-old remedy that provide benefits for bone and joint health and help in bone growth. It is also popular as a post workout joint aid for athletes.

For describing Cissus Quadrangularis, an ancient quote in relation with shape and effect on organ states: "यत्र आकृति: तत्र गुणा: वसंति ।" This implies that as the shape is, thus the qualities shall be.

The Cissus quadrangularis stalk looks a lot like the structure of bone and joint in the body and is very effective in strengthening bones and joints. It is also known as Asthisamharaka, Ashti Shrunkhala, Vajravalli apart from hadjod. Asthisamharaka in Sanskrit means that which saves bones from destruction. Cissus Quadrangularis or hadjod is native to the hotter parts of Ceylon and India. It is prescribed in ancient Ayurvedic texts as a general tonic and analgesic, with specific bone fracture healing properties. Due to all these benefits of cissus, I usually recommend Cissus Quadrangularis capsules by BestSource Nutrition to all patients suffering from bone and joints related problems.

The following points provide in depth knowledge about the Benefits of Cissus Quadrangularis:

Several compounds found in Cissus Quadrangularis have shown improvement in mobility of blast cells of the damaged area.

  • Ketosteron activity:

    Ketosterone is plant sterols (phytochemical) and active ingredient of Cissus Quadrangularis. Ketosterones are a joint aid provided by Cissus Quadrangularis. I always recommend Cissus Quadrangularis capsules by BestSource Nutrition as it is standardized to 5% Ketosterones. Hadjod is a dietary supplement, so its benefits depend on how much standardized ketosterones are present in the supplement capsules.

  • Improved blast cells benefits recovery:

    Cissus Quadrangularis or hadjod acts as a rebuilder of connective tissues. It makes blast cells respond faster to injury, which leads to overall speedy recovery. It is because the benefits of Cissus Quadrangularis supplement includes increasing the retention of calcium, phosphorus, collagen, and mucopolysaccharides. This action of bone mineralization delivers the right building blocks to an injured area for repairs.

  • Bone injury healing:

    Study published in the Research Gate about Cissus Quadrangularis says it increases osteoblast proliferation in the bone tissues of connective tissue. In the study, researchers examined dogs with cracked limbs. In the treatment, they gave Cissus Quadrangularis supplement for bone recovery and found dogs given supplements healed considerably sooner than dogs in the control group. Bone Injury healing is also one of the important benefits of cissus.

  • Lowers joint inflammation:

    High rate of inflammation can damage joints by dilating blood vessels in the affected area. Joint inflammation may have associated joint pain, swelling and sometimes heat. Because of inflammation, myeloperoxidase enzymes are released. This process creates neutrophils toxicity in healthy cells and eliminates them. These healthy cells are needed for recovery of the inflamed area. A study published in J Herb Pharmacother, 2005, about Cissus Quadrangularis extract (CQE) states that hadjod provides benefits through inhibitory action on the generation of lipid peroxidation, pro-inflammatory cytokines and neutrophil infiltration. This can check inflammation in joints.

  • Nature’s gift for athletes:

    People engaging in high volume or intense exercise often feel inflammation-induced joint pain. Cissus Quadrangularis or hadjod has an anti-inflammatory effect. A study by Phys Sportsmed, 2013 has reported therapeutic effects of Cissus Quadrangularis supplement in healthy exercise-trained men with joint pain. In an eight-week course of supplementation with CQE, benefits of reduced joint pain were noted in a sample of 29 young exercise-trained men.

  • Obesity and cardiovascular health:

    Another benefit of hadjod is its ability to maintain body weight. Obesity is generally linked to complications in lipid metabolism and oxidative stress. According to Lipids Health Dis. 2007, a study was done on the effect of Cissus Quadrangularis extract (CQE) on weight, blood lipids, and oxidative stress in overweight and obese people. CQE supplementation was found effective for weight loss and improved cardiovascular health.

The above points show how Cissus Quadrangularis supplements like Cissus Quadrangularis capsules are safe and beneficial. Many safety and toxicology studies have been done on hadjod and no observable side effects have been noted. However, the functionality of Cissus Quadrangularis capsule supplement depends on the ketosterones standardization. Therefore, I only trust Cissus Quadrangularis tablets or capsules provided by BestSource Nutrition. This product is 5% standardized to Ketosterones and completely natural, without any side effects.

Disclaimer: All content provided on this section is for informational purposes only. Any views or opinions or claims represented in this content are personal, belong solely to the writer and do not represent those of people, institutions or organizations that the writer may or may not be associated with in professional or personal capacity, unless explicitly stated. makes no representations as to the accuracy or completeness of any information on this article.

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